Consanguineous Tunisian GEFS+family pedigree. Legend: A. Haplotype reconstruction for markers on chromosome 22q13.31, which are ordered from centromere to telomere. Markers from the Illumina array are in italic. The IBD haplotype shared by family members is shown in solid lines. Recombinaison events are shown by solid drawbar. Maternal and paternal chromosomes are designated by M and P, respectively. Each phenotype is describing by different colors. B. List of markers used for haplotype reconstruction with physical position. Markers from the Illumina array are in italic.