Skip to main content

Table 1 The genotype distribution of rs8050136 and the association with type 2 diabetes risk in Han Chinese

From: Genetic variant in fat mass and obesity-associated gene associated with type 2 diabetes risk in Han Chinese

Genotype

Cases N (%)

Controls N (%)

OR (95% CI)

p-value

OR (95% CI)

p-value

CC

2205 (76.1)

2625 (80.5)

1.00

 

1.00

 

CA

652 (22.5)

602 (18.5)

1.29(1.14–1.46)

6.3Ă—10-5

1.20(1.04–1.38)

0.011

AA

41 (1.4)

35 (1.1)

1.39(0.89–2.20)

0.152

1.11(0.66–1.87)

0.687

CA/AA

693 (23.9)

637 (19.5)

1.30(1.15–1.46)

3.0Ă—10-5

1.19(1.04–1.37)

0.011

Additive

  

1.27(1.13–1.41)

3.8Ă—10-5

1.17(1.03–1.32)

0.016

  1. Genotype was successfully detected in 2,898 T2D cases and 3,262 controls. Odds ratios (95% confidence intervals) and p-values were calculated in the logistic regression model. Results of adjustment for age, sex and body mass index are in bold.