|
Genotype
|
Cases N (%)
|
Controls N (%)
|
OR (95% CI)
|
p-value
|
OR (95% CI)
|
p-value
|
|---|
|
CC
|
2205 (76.1)
|
2625 (80.5)
|
1.00
| |
1.00
| |
|
CA
|
652 (22.5)
|
602 (18.5)
|
1.29(1.14–1.46)
|
6.3×10-5
|
1.20(1.04–1.38)
|
0.011
|
|
AA
|
41 (1.4)
|
35 (1.1)
|
1.39(0.89–2.20)
|
0.152
|
1.11(0.66–1.87)
|
0.687
|
|
CA/AA
|
693 (23.9)
|
637 (19.5)
|
1.30(1.15–1.46)
|
3.0×10-5
|
1.19(1.04–1.37)
|
0.011
|
|
Additive
| | |
1.27(1.13–1.41)
|
3.8×10-5
|
1.17(1.03–1.32)
|
0.016
|
- Genotype was successfully detected in 2,898 T2D cases and 3,262 controls. Odds ratios (95% confidence intervals) and p-values were calculated in the logistic regression model. Results of adjustment for age, sex and body mass index are in bold.
