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Figure 1 | BMC Genetics

Figure 1

From: An EM algorithm based on an internal list for estimating haplotype distributions of rare variants from pooled genotype data

Figure 1

Expected sum of squared errors of various haplotype frequency estimators for a 25 loci case. Expected sum of squared errors of various haplotype frequency estimators (EM-CDL: EM with CD list; EM-ACDL: augmented CD list; EML: EM with combinatorially determined list; CDMLE: collapsed data MLE; EM-TCDL: CD list with trimming and no augmentation; EM-ATCDL: augmented and trimmed CD list; EM-PL: EM with perfect list) based on 100 simulations of (a) n=100 and (b) n=200 pools of k individuals each when the true haplotype distribution over 25 loci is as given in Table 3.

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