From: Association analysis of complex diseases using triads, parent-child dyads and singleton monads
Parental | Affected child | P(MT, C | D) | P(MT | D) | # Obs |
---|---|---|---|---|
mating type | genotype C | |||
1. AA × AA | AA | p^{4}ψ_{ 2 }/R | p^{4}ψ_{ 2 }/R | n _{ 1 } |
2. AA × Aa | AA | 4p^{3}q ψ_{ 2 }/(2R) | 4{p}^{3}q\frac{{\psi}_{1}+{\psi}_{2}}{2R} | n _{ 2 } |
Aa | 4p^{3}q ψ_{ 1 }/(2R) | n _{ 3 } | ||
3. AA × aa | Aa | 2p^{2}q^{2}ψ_{ 1 }/R | 2p^{2}q^{2}ψ_{ 1 }/R | n _{ 4 } |
4. Aa × Aa | AA | 4p^{2}q^{2}ψ_{ 2 }/(4R) | 4{p}^{2}{q}^{2}\frac{{\psi}_{2}+2{\psi}_{1}+1}{4R} | n _{ 5 } |
Aa | 4p^{2}q^{2}(2ψ_{ 1 })/(4R) | n _{ 6 } | ||
aa | 4p^{2}q^{2}/(4R) | n _{ 7 } | ||
5. Aa × aa | Aa | 4p q^{3}ψ_{ 1 }/(2R) | 4p{q}^{3}\frac{{\psi}_{1}+1}{2R} | n _{ 8 } |
aa | 4p q^{3}/(2R) | n _{ 9 } | ||
6. aa × aa | aa | q^{4}/R | q^{4}/R | n _{ 10 } |
Total | 1 | 1 | n |