|
HB (N = 412)
|
Infant Leukemia (N = 392)
|
Combined (N = 804)
|
---|
|
βa(95% CI)
|
% changeb
|
Pvalue
|
βa
|
% changeb
|
Pvalue
|
βa
|
% changeb
|
Pvalue
|
---|
Age at DNA collection (years)
| | | | | | | | |
0 – 2
|
0.60 (−0.27-1.47)
|
81
|
0.18
|
0.81 (−0.37-1.99)
|
125
|
0.18
|
0.67 (−0.09-1.42)
|
95
|
0.08
|
2 – 5
|
−0.10 (−0.65-0.46)
|
−9.1
|
0.74
|
−0.76 (−1.72-0.20)
|
−53
|
0.12
|
−0.42 (−0.97-0.12)
|
−34
|
0.13
|
> 5 years
|
Reference
|
Reference
| |
Reference
|
Reference
| |
Reference
|
Reference
| |
Child’s sex
| | | | | | | | | |
Male
|
Reference
|
Reference
| |
Reference
|
Reference
| |
Reference
|
Reference
| |
Female
|
0.06 (−0.42-0.55)
|
6.6
|
0.80
|
0.47 (−0.35-1.28)
|
60
|
0.26
|
0.31 (−0.17-0.78)
|
36
|
0.21
|
Study
| | | | | | | | | |
HB
|
NA
|
NA
|
NA
|
NA
|
NA
|
NA
|
Reference
|
Reference
| |
Infant leukemia
|
NA
|
NA
|
NA
|
NA
|
NA
|
NA
|
−1.05 (−1.60- -0.51)
|
−65
|
0.0002
|
Case control status
| | | | | | | | |
Control
|
Reference
|
Reference
| |
Reference
|
Reference
| |
Reference
|
Reference
| |
Case
|
−0.65 (−1.18- -0.11)
|
−48
|
0.01
|
−0.64 (−1.52-0.25)
|
−42
|
0.16
|
−0.69 (−1.20- -0.17)
|
−50
|
0.01
|
Collection type
| | | | | | | | | |
Cytosoft brush
|
Reference
|
Reference
| |
Reference
|
Reference
| |
Reference
|
Reference
| |
Epicentre brush
|
0.94 (0.43-1.45)
|
160
|
0.0003
|
2.46 (1.15-3.76)
|
1070
|
0.0002
|
1.23 (0.64-1.81)
|
242
|
<0.0001
|
Mouthwash
|
4.22 (3.26-5.17)
|
6670
|
<0.0001
|
NA
| |
NA
|
4.42 (3.16-5.67)
|
8210
|
<0.0001
|
Maternal race
| | | | | | | | | |
White
|
Reference
|
Reference
| |
Reference
|
Reference
| |
Reference
|
Reference
| |
Other
|
−0.66 (−1.24- -0.08)
|
−49
|
0.03
|
0.36 (−0.75-1.47)
|
43
|
0.52
|
−0.19 (−0.80-0.42)
|
−17
|
0.52
|
Season of DNA collection
| | | | | | | | |
Spring
|
Reference
|
Reference
| |
Reference
|
Reference
| |
Reference
|
Reference
| |
Summer
|
−0.89 (−1.52- -0.26)
|
−59
|
0.006
|
−3.85 (−5.03- -2.66)
|
−97
|
<0.0001
|
−2.06 (−2.71- -1.42)
|
−87
|
<0.0001
|
Fall
|
−0.36 (−1.05-0.33)
|
−30
|
0.31
|
−1.56 (−2.67- -0.45)
|
−79
|
0.006
|
−0.84 (−1.50- -0.19)
|
−57
|
0.01
|
Winter
|
0.01 (−0.67-0.70)
|
1.5
|
0.97
|
1.02 (−0.13-2.17)
|
469
|
0.08
|
0.54 (−0.13-1.22)
|
72
|
0.11
|
- a Models were adjusted for all other variables in table.
- b Percent change in DNA yield compared to referent.