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Table 1 Selected characteristics of the study population

From: Predictors of mother and child DNA yields in buccal cell samples collected in pediatric cancer epidemiologic studies: a report from the Children’s Oncology group

Characteristic

HB study

Infant leukemia study a

N (%)

N (%)

N children with samples

412

392

Median DNA yield (μg)

0.37 (0 – 139)

0.15 (0 – 14)

Child’s age at DNA collection

  

0 – 2 years

45 (11)

75 (19)

2 – 5 years

151 (37)

123 (31)

> 5 years

216 (52)

194 (49)

Child’s sex

  

Male

241 (58)

183 (47)

Female

171 (42)

209 (53)

Case control status

  

Case

246 (60)

223 (57)

Control

166 (40)

169 (43)

Storage (Child’s sample)

  

0 – 3 days

108 (29)

121 (46)

3 – 7 days

99 (26)

64 (24)

7 – 14 days

92 (24)

54 (21)

> 14 days

79 (21)

23 (9)

Season of DNA collection

  

Spring

119 (29)

117 (30)

Summer

117 (28)

80 (20)

Fall

90 (22)

109 (28)

Winter

86 (21)

86 (22)

Sample collection

  

Cytosoft brush

175 (42)

341 (87)

Epicentre brush

202 (49)

51 (13)

Mouthwash

35 (9)

 

N Mothers with samples

446

489

Median DNA yield (μg)

14 (0.02 – 401)

14 (0.06 – 1209)

Mother’s age at DNA collection

  

< 30 years

89 (20)

104 (21)

30 – 35 years

117 (26)

147 (30)

35 – 40 years

131 (29)

134 (27)

> 40 years

109 (24)

104 (21)

Storage (Mother’s sample)a

  

0 – 3 days

110 (27)

121 (38)

3 – 7 days

126 (31)

104 (33)

7 – 14 days

100 (25)

57 (18)

> 14 days

68 (17)

35 (11)

Maternal education

  

< High School

31 (7)

26 (5)

High School

74 (17)

104 (21)

Some college

115 (26)

146 (30)

College degree

158 (35)

152 (31)

Advanced degree

68 (15)

61 (13)

Maternal race

  

White

349 (78)

411 (84)

Black

18 (4)

19 (4)

Hispanic

50 (11)

30 (6)

Asian

18 (4)

16 (3)

Other

11 (2)

13 (3)

Income

  

< $20,000

65 (15)

73 (15)

$20,000 -- $50,000

122 (28)

183 (38)

$50,000 -- $75,000

102 (23)

110 (23)

>%75,000

153 (35)

122 (25)

Season of DNA collection

  

Spring

128 (29)

138 (28)

Summer

126 (28)

100 (20)

Fall

98 (22)

140 (29)

Winter

94 (21)

111 (23)

  1. a N’s may not sum to total due to missing data. Storage time missing for 34 children in the HB study, 130 children in infant leukemia study, 42 mothers in HB study, and 172 mothers in the infant leukemia study. Income data were missing for 4 mothers in the HB study and 1 mother in the infant leukemia study.