Table 1 Genotypes at the three previously undescribed rare variants in ROCK1 in case and control populations
From: Low-frequency intermediate penetrance variants in the ROCK1 gene predispose to Tetralogy of Fallot
Cases | Controls | Trend p-value | |||||
|---|---|---|---|---|---|---|---|
Variant | Homozygote major allele | Heterozygote | Homozygote minor allele | Homozygote major allele | Heterozygote | Homozygote minor allele | |
rs56085230 | 445 | 12 | 0 | 1283 | 5 | 0 | 0.006 |
c.1785 T > G | 452 | 5 | 0 | 1309 | 10 | 0 | 0.49 |
p.Thr773Ser | 441 | 17 | 0 | 1285 | 46 | 0 | 0.77 |