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Table 5 Dnd1 genotype and occurrence of males affected with at least one spontaneous TGCT

From: Contrasting effects of Deadend1 (Dnd1) gain and loss of function mutations on allelic inheritance, testicular cancer, and intestinal polyposis

Genotype

Affected

Unaffected

Affected males (%)

Dnd1 +/+

8

121

*6%

Dnd1 +/KO

7

109

*6%

Ç‚Dnd1+/Ter

35

90

39%

  1. Dnd1+/KO males are offspring of both Dnd1+/+ × Dnd1+/KO and Dnd1+/KO × Dnd1+/+ reciprocal crosses. ǂ Results from Zechel et al.[51].