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Table 3 Dnd1 +/KO segregation in backcrosses versus intercrosses

From: Contrasting effects of Deadend1 (Dnd1) gain and loss of function mutations on allelic inheritance, testicular cancer, and intestinal polyposis

Cross

No. Dnd1+/+

No. Dnd1+/KO *(expectations)

% expected number

Litter size

Intercross

120

162 (240)

67.5

5.6±0.5 n=18

Backcross:maternal

110

107 (110)

97.2

5.8±0.4 n=30

Backcross:paternal

100

96 (100)

96

5.2±0.4 n=19

  1. Dnd1KO segregation in intercrosses and backcrosses. Results are presented after pooling data for both genders (Tables 1, 2, 3, 4), because occurrence of females and males did not differ significantly (not shown).
  2. *Mendelian expectations based on Dnd1+/+; litter size (mean ± SEM, n is the number of litters).
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BMC Genomic Data

ISSN: 2730-6844

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