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Table 2 Dnd1 +/KO intercross – genotype distribution at embryonic day 3.5 (E3.5)

From: Contrasting effects of Deadend1 (Dnd1) gain and loss of function mutations on allelic inheritance, testicular cancer, and intestinal polyposis

Genotype

Observed

Mendelian expectations

Dnd1 +/+

16

6.25

Dnd1 +/KO

9

12.5

Dnd1 KO/KO

0

6.25

  1. Dnd1KO segregation in intercrosses and backcrosses. Results are presented after pooling data for both genders (Tables 1, 2, 3, 4), because occurrence of females and males did not differ significantly (not shown).