Table 3 False positive and true positive rates via TotD| M , when v / μ is not known in advance, under expanding population (with correct r )
From: Detecting negative selection on recurrent mutations using gene genealogy
A. r=2.6 × 10-3 | ||||
|---|---|---|---|---|
θ μ | σ=0 (neutral) | σ = − 103/2 | σ = − 102 | σ = − 105/2 |
10-1 | 0.185 | 0.125 | NA a | NA |
10-1/2 | 0.179 | 0.315 | 0.500 | NA |
1(=100) | 0.095 | 0.184 | 0.352 | 0.600 |
10+1/2 | 0.056 | 0.141 | 0.340 | 0.580 |
10+1 | 0.018 | 0.058 | 0.283 | 0.551 |
B. r=4.0 × 10-3 | ||||
θ μ | σ = 0 (neutral) | σ = − 103/2 | σ = − 102 | σ = − 105/2 |
10-1 | 0.341 | 0.333 | NA a | NA |
10-1/2 | 0.265 | 0.259 | 0.516 | NA |
1(=100) | 0.187 | 0.258 | 0.509 | 0.886 |
10+1/2 | 0.081 | 0.210 | 0.491 | 0.818 |
10+1 | 0.026 | 0.115 | 0.408 | 0.668 |
C. r=5.7 × 10-3 | ||||
θ μ | σ=0 (neutral) | σ = − 103/2 | σ = − 102 | σ = − 105/2 |
10-1 | 0.372 | 0.583 | 0.833 | NA a |
10-1/2 | 0.288 | 0.376 | 0.680 | NA |
1(=100) | 0.236 | 0.423 | 0.655 | 0.957 |
10+1/2 | 0.080 | 0.252 | 0.524 | 0.780 |
10+1 | 0.022 | 0.119 | 0.401 | 0.607 |