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Table 5 Summary of single QTL scans in BC- A y mice

From: Genetic background (DDD/Sgn versus C57BL/6J) strongly influences postnatal growth of male mice carrying the Ayallele at the agouti locus: identification of quantitative trait loci associated with diabetes and body weight loss

Trait Chromosome Location (cM)a 95% CI (cM)b Max LODc Nearest marker High alleled
Body weight at 25 weeks 1 56 45–73 2.69* D1Mit102 B6
  4 61 41–61 4.25* D4Mit234 B6
  6 44 0–56 1.44 D6Mit108 B6
  15 80 0–80 1.39 D15Mit193 DDD
BMI 1 56 0–73 1.48 D1Mit102 B6
  4 55 36–61 4.77* D4Mit234 B6
  6 45 0–56 2.16 D6Mit256 B6
Blood glucose 4 61 21–61 1.88 D4Mit234 DDD
  7.1 0 na 1.54 D7Mit250 B6
  12 30 0–49 1.82 D12Mit259 B6
Plasma glucose 4 61 13–65 1.55 D4Mit234 DDD
  7.1 0 na 1.56 D7Mit250 B6
  12 30 10–49 2.28 D12Mit259 B6
  19 11 0–35 1.73 D19Mit32 DDD
Plasma triglyceride 8 14 0–28 1.77 D8Mit249 DDD
  12 27 7–44 2.39 D12Mit259 DDD
  18 0 0–71 1.42 D18Mit21 DDD
HMW adiponectin 4 39 10–61 1.89 D4Mit12 B6
  7.1 0 na 1.57 D7Mit250 DDD
  1. aLocation indicates a chromosomal position showing a peak LOD score in cM.
  2. b95% CI is defined by a 1.5-LOD support interval. na, not available.
  3. cMaximum LOD score for QTL. Significant QTLs are indicated by * (suggestive QTLs are shown without asterisks).
  4. dAllele associated with higher trait values.