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Table 4 Phenotypes of BC males

From: Genetic background (DDD/Sgn versus C57BL/6J) strongly influences postnatal growth of male mice carrying the Ayallele at the agouti locus: identification of quantitative trait loci associated with diabetes and body weight loss

Phenotype at 25 weeks

Mean ± SE values (range)

BC non-Aymales (n = 96)

BC Aymales (n = 100)

Body weight (g)

43.64 ± 0.59

49.37 ± 0.51

(33.05–57.90)

(36.13–60.28)

BMI

4.00 ± 0.04

4.48 ± 0.04

(3.22–4.94)

(3.61–5.31)

Blood glucose (mg/dl) a

209.1 ± 4.4

329.7 ± 14.9

(115–379)

(110–600)

Plasma glucose (mg/dl)

nd

427.3 ± 18.6

 

(164–869)

Total-cholesterol (mg/dl)

121.7 ± 2.7

154.0 ± 4.4

(69–198)

(74–303)

Triglyceride (mg/dl)

245.2 ± 9.9

622.0 ± 24.7

(98–778)

(109–1,247)

HMW adiponectin (μg/ml)

nd

3.81 ± 0.13

 

(1.67–9.15)

  1. aSeven mice had blood glucose levels that exceeded the upper limit of the measuring method (600 mg/dl). Therefore, mean ± SE values were calculated by assuming that their blood glucose levels were 600 mg/dl.
  2. Values are significantly greater in BC Ay than in BC non-Ay males. nd, not determined.