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Figure 3 | BMC Genetics

Figure 3

From: Genetic background (DDD/Sgn versus C57BL/6J) strongly influences postnatal growth of male mice carrying the Ayallele at the agouti locus: identification of quantitative trait loci associated with diabetes and body weight loss

Figure 3

Comparison of blood phenotypes at 25 weeks of age after 4 h of fasting in parental and F 1 mouse strains. (A) Blood glucose levels, (B) plasma triglyceride levels, (C) plasma total-cholesterol levels, and (D) plasma HMW adiponectin levels. Error bars indicate standard errors. The sample sizes of mice for glucose, triglyceride, and total-cholesterol determination was the same as those in Table 1. HMW adiponectin levels were determined in 7–10 mice for each strain. Males and females were analyzed separately. All pairs were compared by Tukey–Kramer HSD tests; however, the results of statistical comparisons are shown only for those related to DDD-Ay males. A, Significant difference (P <0.0001) versus DDD, B6-Ay, B6, (DDD × B6) F1, (B6 × DDD) F1-Ay, and (B6 × DDD) F1. NS, no significant difference between DDD-Ay and (DDD × B6) F1-Ay. B, Significant difference (P <0.0001) versus B6-Ay, B6, (DDD × B6) F1, (B6 × DDD) F1-Ay, and (B6 × DDD) F1, and significant difference (P <0.002) versus DDD. NS, no significant difference between DDD-Ay and (DDD × B6) F1-Ay. C, Significant difference (P <0.01) versus DDD and B6-Ay. D, Significant difference (P <0.0001) versus B6-Ay, and significant difference (P <0.05) versus DDD and B6.

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