Table 4 Positional candidate genes (PCG) within 1-Mb SNP window (SNPW) and their putative functions
From: Genome-wide association study of infectious bovine keratoconjunctivitis in Angus cattle
| Chromosome | SNPW | PCG | Gene ontology |
|---|---|---|---|
| 2 | 19.11 - 19.97 | AGPS | It encodes a protein that catalyzes the step of lipid biosynthesis |
| and the removal of long chain acid anion | |||
| NFE2L2 | It encodes a transcription factor which is a member of a small | ||
| family of basic Leucine (bZIP) proteins | |||
| 2 | 22.09 - 22.77 | WIPF1 | It encodes a protein that plays an important role in the organization |
| of the actin cytoskeleton | |||
| OLA1 | It hydrolyzes ATP and can hydrolyze GTP with lower efficiency | ||
| SP3 | regulates transcription by binding consensus GC and GT- box | ||
| elements in target genes | |||
| 12 | 53.01 - 53.99 | SCEL | It encodes a tissue-specific basic helix-loop-helix (bHLH) protein |
| with a pivotal role in hemopoises | |||
| EDNRB | it mediates actin by association with G-Protein that activates | ||
| a phosphaidylinositol-calcium second messenger system | |||
| 13 | 14.36 - 14.92 | VAMP7 | It encodes a transmembrane protein that is a member of soluble |
| N-ethylmeleimide-sensitive factor attachment protein receptor | |||
| (SNARE) family | |||
| 21 | 19.00 - 19.98 | NTRK3 | It encodes a member of a neurotrophic tyrosine receptor kinase family |
| MIR1179 | It involved in post transcriptional regulation of gene expression | ||
| MIR7-1 | It involved in post transcriptional regulation of gene expression |