Fine-scale mapping of meiotic recombination in Asians

BMC Genomic Data

Table 3 Summary of cohort results

	Mongolian	Korean	CEPH families
Number of SNP markers	569132	516452	931633
Meioses	254	722	234
Total crossovers detected	8776	24355	8093
Average male recombination rate	27.43	25.84	26.49
Average female recombination rate	41.96	40.75	42.90
Median resolution (bp)	83525	114681	74169
Historical hotspot concordance	0.83	0.81	0.82
Concordance of randomly placed intervals	0.36	0.37	0.35
Estimated true historical hotspot usage	0.74	0.70	0.72

Summary of results for the three cohorts. We do not find the differences in recombination rate or historical hotspot concordance significant. Historical hotspot concordance records the overlap rate of crossovers resolved to 30 kb or better. ‘Randomly placed intervals’ are generated by random perturbations of well-resolved crossovers following a normal distribution (μ = 0; σ = 200 kb). The Mongolian and Korean results were combined to form our Asian genetic map.

ISSN: 2730-6844