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Table 3 Additive value of minor allele for FLNB variants associated with BMD Z-score in this and our previous study

From: Conditional testing of multiple variants associated with bone mineral density in the FLNB gene region suggests that they represent a single association signal

SNP BMD Z-score phenotype Additive value of minor allele P
rs11720285 Femoral neck + 0.306 (366) 0.03
  Total hip + 0.274 (373) 0.053
rs7637505† Femoral neck + 0.287 (422) 0.031
  Total hip + 0.262 (434) 0.033
rs11130605 Femoral neck + 0.241 (575) 0.045
  Total hip + 0.268 (592) 0.03
rs9809315 Femoral neck + 0.304 (435) 0.014
  Total hip + 0.254 (448) 0.045
rs9822918† Femoral neck + 0.397 (650) 0.002
  Total hip + 0.414 (668) 0.002
rs2177153† Femoral neck + 0.537 (459) 0.0004
  Total hip + 0.443 (474) 0.001
rs2001972† Femoral neck + 0.254 (547) 0.043
  Total hip + 0.264 (563) 0.041
  1. Results are given as additive effect on the trait of the minor allele relative to the more common allele (number of alleles included in analysis), derived from UNPHASED v3.1.5.
  2. †Variant genotyped in our previous study [24].
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BMC Genomic Data

ISSN: 2730-6844

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