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Table 3 Additive value of minor allele for FLNB variants associated with BMD Z-score in this and our previous study

From: Conditional testing of multiple variants associated with bone mineral density in the FLNB gene region suggests that they represent a single association signal

SNP

BMD Z-score phenotype

Additive value of minor allele

P

rs11720285

Femoral neck

+ 0.306 (366)

0.03

 

Total hip

+ 0.274 (373)

0.053

rs7637505†

Femoral neck

+ 0.287 (422)

0.031

 

Total hip

+ 0.262 (434)

0.033

rs11130605

Femoral neck

+ 0.241 (575)

0.045

 

Total hip

+ 0.268 (592)

0.03

rs9809315

Femoral neck

+ 0.304 (435)

0.014

 

Total hip

+ 0.254 (448)

0.045

rs9822918†

Femoral neck

+ 0.397 (650)

0.002

 

Total hip

+ 0.414 (668)

0.002

rs2177153†

Femoral neck

+ 0.537 (459)

0.0004

 

Total hip

+ 0.443 (474)

0.001

rs2001972†

Femoral neck

+ 0.254 (547)

0.043

 

Total hip

+ 0.264 (563)

0.041

  1. Results are given as additive effect on the trait of the minor allele relative to the more common allele (number of alleles included in analysis), derived from UNPHASED v3.1.5.
  2. †Variant genotyped in our previous study [24].