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Table 4 Summary of single QTL scans for combined F 2 mice using the agouti genotypes as covariates

From: Quantitative trait locus mapping of genes associated with vacuolation in the adrenal X-zone of the DDD/Sgn inbred mouse

Chromosome

LOD scores[peak position (cM),name]

 

agouti as an additive covariate (LODa)a

agouti as an interactive covariate (LODf)b

LODi(LODf-LODa)c

1

4.03 (36, Xzvdq1)

  

2

5.42 (80, Xzvdq2)

6.03 (82, Xzvdq2)

 

6

11.22 (65, Xzvdq4)

11.89 (65, Xzvdq4)

 

8

 

4.52 (24, Xzvdq6)

3.84 (23, Xzvdq6)

  1. Only significant QTLs are listed.
  2. a, Significant threshold LOD scores are 3.37 for autosomes and 2.76 for X chromosome.
  3. b, Significant threshold LOD scores are 4.39 for autosomes and 3.43 for X chromosome.
  4. c, LODi is the difference between the LOD score with agouti as an interactive covariate (LODf) and the LOD score with agouti as an additive covariate (LODa). It concerns the test of the QTL × agouti interaction. Significant threshold LOD scores are 2.41 for autosomes and 3.12 for X chromosome.
  5. See also Figure5.