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Table 3 Comparison of the haplotype frequencies in the GSTA gene cluster of the populations from Tver, Murom, and Kursk with those from the HapMap Project (CEU, CHB, JPT, and YRI) *

From: Analysis of DNA variations in GSTA and GSTMgene clusters based on the results of genome-wide data from three Russian populations taken as an example

 

MUROM

KURSK

СЕU

CHB

JPT

YRI

Number of haploblock

The level of significance

TVER

0,6746

0,8353

0,8534

<0,0001

<0,0001

0,0269

I

0,004

 

0,9599

0,4282

0,6984

<0,0001

<0,0001

<0,0001

II

0,0025

 

0,9030

0,3306

0,0403

<0,0001

<0,0001

<0,0001

III

0,0025

 

0,8238

0,2076

0,0326

<0,0001

<0,0001

0,0065

IV

0,0019

 

0,0484

0,3957

0,2428

0,6452

V

0,0025

 

0,4538

0,9276

0,4634

VI

0,0025

MUROM

 

0,4641

0,4574

<0,0001

<0,0001

<0,0001

I

0,004

  

0,5661

0,5307

<0.0001

<0.0001

<0,0001

II

0,0025

  

0,1764

0,1188

<0.0001

<0.0001

<0,0001

III

0,0025

  

0,1599

0,0408

<0,0001

<0,0001

0,0006

IV

0,0019

  

0,5052

0,5524

0,0031

V

0,0025

  

0,2664

0,8195

VI

0,0025

KURSK

  

0,9266

<0,0001

<0,0001

0,0097

I

0,004

   

0,1321

<0.0001

<0.0001

<0,0001

II

0,0025

   

0,0013

<0.0001

<0.0001

<0.0001

III

0,0025

   

0,2053

<0,0001

<0,0001

0,0006

IV

0,0019

   

0,9682

0,1181

V

0,0025

   

0,2694

VI

0,0025

  1. * Pairwise P-values are presented. The last column contains Bonferroni adjusted P-values calculated for each block. The calculations was performed using the formula P = 0.05/ ([n × a] – 1), where “n” is the number of haplotypes and “a” is the number of populations [16]. The absence of some haploblocks in the CHB, JPT, and YRI populations did not allow us to compare these populations; the respective columns are marked with dashes on the corresponding lines.