Table 1 Body and fat pad weights of B6.TH- tabw2 congenic, subcongenic, and B6-homozygous control mice on chow and high fat-high sucrose diets (HFS) (males)

Control

0

0

28.7 ± 0.4^a (n = 15)

29.6 ± 0.7^d (n = 17)

0.81 ± 0.06^c (n = 15)

1.77 ± 0.27^c (n = 17)

tabw2

140.1

112.3

28.4 ± 0.5^ab (n = 13)

36.9 ± 1.1^a (n = 7)

1.15 ± 0.07^a (n = 13)

5.22 ± 0.42^a (n = 7)

Line A

57.9

39.9

27.4 ± 0.4^bc (n = 19)

29.8 ± 0.9^cd (n = 11)

0.85 ± 0.06^bc (n = 19)

2.87 ± 0.33^b (n = 11)

Line B

92.5

57.2

27.2 ± 0.5^bc (n = 11)

31.3 ± 0.8^bcd (n = 14)

1.16 ± 0.07^a (n = 11)

2.74 ± 0.30^b (n = 14)

Line C

45.1

30.7

26.9 ± 0.3^c (n = 29)

32.2 ± 0.6^b (n = 28)

0.99 ± 0.05^ab (n = 29)

2.70 ± 0.21^b (n = 28)

Line D

10.8

1.4

28.5 ± 0.3^a (n = 33)

31.7 ± 0.5^bc (n = 40)

0.95 ± 0.04^bc (n = 33)

2.49 ± 0.18^b (n = 40)

ANOVA p-value

0.0007

<0.0001

0.0003

<0.0001