TY - JOUR AU - Estruch, Francisco AU - Hodge, Christine AU - Gómez-Navarro, Natalia AU - Peiró-Chova, Lorena AU - Heath, Catherine V. AU - Cole, Charles N. PY - 2012 DA - 2012/09/10 TI - Insights into mRNP biogenesis provided by new genetic interactions among export and transcription factors JO - BMC Genetics SP - 80 VL - 13 IS - 1 AB - The various steps of mRNP biogenesis (transcription, processing and export) are interconnected. It has been shown that the transcription machinery plays a pivotal role in mRNP assembly, since several mRNA export factors are recruited during transcription and physically interact with components of the transcription machinery. Although the shuttling DEAD-box protein Dbp5p is concentrated on the cytoplasmic fibrils of the NPC, previous studies demonstrated that it interacts physically and genetically with factors involved in transcription initiation. SN - 1471-2156 UR - https://doi.org/10.1186/1471-2156-13-80 DO - 10.1186/1471-2156-13-80 ID - Estruch2012 ER -