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Table 2 Association analysis of 6 high-LD-group tagging SNPs with five hematological traits by linear regression analysis, controlling for area, age, and sex as covariates

From: Association between the ABO locus and hematological traits in Korean

    

WBC

RBC

Plat

MCV

MCHC

CHR

SNP

BP

A1

BETA ± SE

P

BETA ± SE

P

BETA ± SE

P

BETA ± SE

P

BETA ± SE

P

9

rs2073823

135122337

A

0.056 ± 0.039

0.15

0.036 ± 0.008

2.13 × 10-6†

−1.213 ± 1.253

0.33

−0.480 ± 0.118

5.06 × 10-5†

0.075 ± 0.029

9.55 × 10-3

9

rs8176720

135122694

C

0.043 ± 0.032

0.19

0.018 ± 0.006

5.58 × 10-3

−0.232 ± 1.033

0.82

−0.071 ± 0.098

0.47

0.025 ± 0.024

0.30

9

rs8176717

135122855

T

0.001 ± 0.039

0.97

−0.012 ± 0.008

0.13

0.885 ± 1.253

0.48

0.356 ± 0.118

2.62 × 10-3†

−0.035 ± 0.029

0.22

9

rs687289

135126927

A

0.001 ± 0.032

0.97

0.001 ± 0.006

0.89

1.017 ± 1.025

0.32

−0.274 ± 0.097

4.59 × 10-3

0.020 ± 0.024

0.40

9

rs8176681

135129575

C

0.016 ± 0.035

0.64

0.009 ± 0.007

0.19

−1.488 ± 1.109

0.18

0.063 ± 0.105

0.55

0.003 ± 0.026

0.92

9

rs495828

135144688

T

−0.050 ± 0.037

0.18

−0.030 ± 0.007

2.69 × 10-5†

2.217 ± 1.180

0.06

0.061 ± 0.112

0.58

−0.042 ± 0.027

0.12

  1. Note. Chr: chromosome, BP: base pair, A1: minor allele, WBC: white blood cell count, RBC: red blood cell count, Platelet, MCV: mean corpuscular volume, MCHC: mean corpuscular hemoglobin concentration.
  2. Underlined p-values were passed the multiple correction criteria of Bonferroni correction (p<0.008).
  3. Significant result after adjusted by rs2073823.