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Figure 1 | BMC Genetics

Figure 1

From: Pseudogenization of the MCP-2/CCL8 chemokine gene in European rabbit (genus Oryctolagus), but not in species of Cottontail rabbit (Sylvilagus) and Hare (Lepus)

Figure 1

The rabbit ortholog of human CCL7 gene exists and is transcribed. The “A11 isoform 1” predicted by GenBank suggests that exon1 of the Rabbit ortholog of CCL7 uses preferentially exon2 and exon3 of CCL11 during transcription (Additional file 2). We show that cDNA of the leporid species (Oryctolagus cuniculus, Lepus granatensis and Lepus europaeus) contain a transcript uniting three exons orthologous to those of human CCL7 gene. The position of missing MCP-3 characteristic N-glycosylation site is underlined (N X S in other mammals). Variable amino acid residues are highlighted in gray.

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