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Table 8 Simulated genetic architecture of traits

From: Multiple trait multiple interval mapping of quantitative trait loci from inbred line crosses

     Effects of each QTLd e f
Scenarioa   h2b u c Q1 Q2 Q3 Q4 Q5 T1 T2 T3
  T1 0 30 0 0 0 0 0 1 0.2 0
S0 T2 0 35 0 0 0 0 0 0.2 1 -0.2
  T3 0 30 0 0 0 0 0 0 -0.2 1
  T1 25 30 0.52 0.52 0.52 0.52 0.52 1 0.2 0
  T2 25 35 0.52 0.52 0.52 0.52 0.52 0.2 1 -0.2
SI T3 25 30 0.52 0.52 0.52 0.52 0.52 0 -0.2 1
  Chr. 1 2 3 5 6
  Positione 23 15 45 67 53
  T1 25 30 0.52 0.52 0.52 0.52 0.52 1 0.2 0
  T2 18 35 0 0.54 0.54 0.54 0 0.2 1 -0.2
SII T3 5 30 0 0 0.46 0 0 0 -0.2 1
  Chr. 1 2 3 5 6
  Position 23 15 45 67 53
  T1 18 30 0.54 0 0.54 0 0.54 1 0.2
  T2 18 35 0 0.54 0.54 0.54 0 0.2 1
SIII Chr. 1 1 3 6 6
  Position 23 33 45 38 53
  1. Simulated genetic architecture of traits T1, T2, and T3, as dictated by QTL Q1, Q2, Q3, Q4, and Q5.
  2. a Scenario S0 is for type I error evaluation. Scenarios SI, SII and SIII are for model fitting evaluations.
  3. b Heritability (%) due to all QTL affecting a trait.
  4. c General mean of each trait.
  5. d Main effect of QTL. The percentage of phenotypic variation of each trait due to each QTL is 5%.
  6. e Position, in cM, of the QTL from the leftmost marker in the chromosome (Chr).
  7. f Residual variance-covariance matrix.