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Table 6 Estimates of QTL position and main effect on PC1 and ADJPC1 of BM data

From: Multiple trait multiple interval mapping of quantitative trait loci from inbred line crosses

 

MIM

MTMIM (GEM-NR)

MTMIM (ECM)

 

PC1

ADJPC1

(PC1 and ADJPC1)

(PC1 and ADJPC1)

QTL

p Ì‚ a

β ̂ 1

p Ì‚

β ̂ 2

p Ì‚

β ̂ 1

β ̂ 2

β ̂ 1

β ̂ 2

Chromosome X

1

1

0.0020

1

0.0165

1

0.0021

0.0175

0.0021

0.0175

2

20

0.0018

20

0.0284

20

0.0017

0.0275

0.0017

0.0275

Chromosome 2

3

–

–

1

0.0304

1

0.0007

0.0293

0.0007

0.0293

4

14

0.0018

17

0.0215

17

0.0018

0.0220

0.0018

0.0220

5

26

0.0017

30

0.0141

29

0.0012

0.0146

0.0011

0.0146

6

71

0.0016

–

–

70

0.0017

-0.0048ns

0.0017

-0.0048ns

7

111

0.0009

116

0.0147

116

0.0011

0.0176

0.0011

0.0177

8

144

0.0012

144

0.0091

144

0.0011

0.0082

0.0011

0.0082

Chromosome 3

9

5

0.0013

–

–

4

0.0011

0.0107

0.0011

0.0107

10

17

0.0022

16

0.0503

17

0.0022

0.0427

0.0022

0.0426

11

48

0.0033

44

0.0279

45

0.0027

0.0253

0.0027

0.0254

12

–

–

54

0.0235

54

0.0007ns

0.0255

0.0007

0.0254

13

82

0.0033

83

0.0391

83

0.0034

0.0394

0.0034

0.0394

14

112

0.0009

116

0.0324

115

0.0009

0.0257

0.0009

0.0257

15

129

0.0015

–

–

128

0.0012

0.0094ns

0.0012

0.0094ns

16

147

0.0007

146

0.0116

145

0.0009

0.0092

0.0009

0.0092

17

169

0.0021

166

0.0268

167

0.0021

0.0273

0.0021

0.0273

Total QTL

15

 

14

 

17

    

∑ ̂ p

     

2.761

31.73

  
      

31.73

521.6

  

∑ ̂ g

2.358

 

–

  

2.369

31.48

  
 

–

 

453.0

  

31.48

453.2

  
  1. Estimates of QTL position ( p ̂ ) and main effect on PC1 ( β ̂ 1 ) and ADJPC1 ( β ̂ 2 ) in the MIM and MTMIM models of BM data with 10% genome-wide significance level. QTL effects in the MTMIM model were estimated via GEM-NR and ECM algorithms. Estimated phenotypic ( ∑ ̂ p ) and genotypic ( ∑ ̂ g ) variance-covariance matrices (multiplied by 105 ) are also shown.
  2. a Estimated position (cM) of QTL from the leftmost genetic marker on the chromosome.
  3. ns Nonsignificant main effect tested with the LRT and 5% significance level. The critical value of the LRT was obtained from the chi-squared distribution function with one degree of freedom.