Efficiency of genomic selection using Bayesian multi-marker models for traits selected to reflect a wide range of heritabilities and frequencies of detected quantitative traits loci in mice

Table 3 Estimated variance components and heritabilities for physiological traits

Trait¹	Model²	$σ^{2} {_{p}}^{3}$	$σ^{2}_{c}$	$σ^{2}_{e}$	$h^{2}_{u}$	$h^{2}_{a}$
	(1)	212.0 _{196.7–229.8}	42.3 _28.4–56.5	148.0 _{131.3–164.1}	0.10 _0.01–0.19	-
	(2) 100%	211.1 _{196.3–227.3}	44.5 _32.0–58.1	152.5 _{139.8–165.1}	-	0.07 _0.05–0.08
	(2) 10%	210.6 _{194.0–225.8}	46.3 _32.4–59.8	154.5 _{141.2–167.6}	-	0.05 _0.00–0.08
HC	(2) 2.5%	210.5 _{194.7–226.5}	46.8 _33.2–60.9	155.8 _{143.7–169.6}	-	0.04 _0.00–0.07
	(3) 100%	213.7 _{196.1–229.6}	40.9 _27.9–54.8	145.4 _{128.9–162.0}	0.08 _0.01–0.17	0.05 _0.04–0.06
	(3) 10%	212.8 _{196.6–229.8}	41.6 _27.9–55.3	147.2 _{130.1–162.7}	0.08 _0.00–0.18	0.03 _0.00–0.06
	(3) 2.5%	212.9 _{197.0–229.7}	41.0 _27.7–54.7	146.3 _{130.1–162.3}	0.10 _0.00–0.18	0.02 _0.00–0.05
	(1)	806.8 _{743.4–873.9}	201.9 _{150.4–261.2}	475.4 _{413.6–534.5}	0.16 _0.07–0.26	-
	(2) 100%	811.5 _{753.5–876.4}	215.4 _{162.3–272.0}	502.4 _{461.6–547.2}	-	0.12 _0.09–0.14
	(2) 10%	798.9 _{737.0–860.1}	225.1 _{169.7–279.2}	517.7 _{476.1–562.3}	-	0.07 _0.03–0.11
I75	(2) 2.5%	798.4 _{736.6–858.0}	231.0 _{174.1–285.9}	525.4 _{485.3–569.4}	-	0.05 _0.02–0.08
	(3) 100%	814.9 _{751.4–878.1}	199.6 _{147.2–257.5}	474.1 _{419.6–529.8}	0.08 _0.02–0.17	0.09 _0.07–0.11
	(3) 10%	803.6 _{739.9–867.1}	204.2 _{148.9–262.2}	487.6 _{429.5–544.9}	0.08 _0.00–0.17	0.06 _0.02–0.10
	(3) 2.5%	806.4 _{741.2–869.7}	197.9 _{143.2–251.3}	474.6 _{413.5–535.3}	0.13 _0.03–0.22	0.04 _0.01–0.07

1. HC = Hematocrit percentage (observations multiplied by 10^-2); I75 = Insulin level (observations multiplied by 10²).
2. Model: (1) = polygenic; (2) = genomic; (3) = polygenic and genomic; with 100/10/2.5% of the markers allowed to have an effect.
3. $σ^{2}_{p}$ : estimates of the total phenotypic variances.
4. $σ^{2}_{c}$ : estimates of variances attributed to the cage effect.
5. $σ^{2}_{e}$ : estimates of residual variances.
6. $h^{2}_{u}$ : heritability based on the polygenic effect.
7. $h^{2}_{a}$ : proportion of the variance attributed to the genomic effect.

ISSN: 2730-6844