Genome-wide linkage analyses identify Hfhl1 and Hfhl3 with frequency-specific effects on the hearing spectrum of NIH Swiss mice

Table 2 QTL influencing DPOAE in C3H-N2 mice

Trait	Marker	Chr	LRS (LOD)	pValue	Effect
PC1	rs6181382	6	8.5 (1.84)	0.00353	3%
	rs6228386	7	21.2 (4.61)	<0.00001	7%
	rs3709825	9	14.1 (3.06)	0.00017	5%
	rs3023429	15	7 (1.51)	0.00813	2%
	rs6358426	18	8.7 (1.89)	0.00316	3%
HFEA	rs13477127	3	7.7 (1.67)	0.00547	3%
	rs6228386	7	24.2 (5.25)	<0.00001	8%
	rs13480323	9	19.4 (4.21)	0.00001	6%
	rs3023429	15	7.9 (1.97)	0.00482	3%
	rs6358426	18	9.1 (1.97)	0.00255	3%
5–9 kHz	rs3658401	5	12.7 (2.75)	0.00037	4%
	rs13480208	9	11.9 (2.58)	0.00057	4%
	rs3698545	14	11.5 (2.49)	0.00070	4%
10–14 kHz	rs13477504	3	7 (1.51)	0.00819	2%
	rs13479082	6	8.5 (1.84)	0.00347	3%
20–24 kHz	gnf01.037.906	1	7.2 (1.56)	0.00723	2%
	rs3724711	7	6.8 (1.47)	0.00901	2%
	rs6207781	9	8.6 (1.87)	0.00342	3%
25–29 kHz	rs13476259	1	7.5 (1.63)	0.00634	3%
	rs6181382	6	7.5 (1.63)	0.00626	3%
	rs3724711	7	16.4 (3.56)	0.00005	5%
	rs6207781	9	9.6 (2.08)	0.00199	3%
30–34 kHz	rs13478952	6	7.3 (1.58)	0.00674	2%
	rs3724711	7	23.8 (5.16)	<0.00001	8%
	rs13480323	9	7.2 (1.56)	0.00746	2%
35–39 kHz	rs3688780	3	11.4 (2.47)	0.00074	4%
	rs6160140	7	16.9 (3.67)	0.00004	6%
	rs13480323	9	18.4 (3.99)	0.00002	6%
	rs3023429	15	8.1 (1.76)	0.00432	3%
	rs6358426	18	7.3 (1.58)	0.00683	2%
40–44 kHz	rs3688780	3	11.1 (2.41)	0.00087	4%
	rs13477669	4	7.5 (1.63)	0.00603	3%
	rs6228386	7	13.8 (2.99)	0.00020	5%
	rs13480323	9	17.1 (3.71)	0.00004	6%
	rs3023429	15	8 (1.74)	0.00473	3%
45–49 kHz	rs13482141	14	9.4 (2.04)	0.00216	3%
	rs3023429	15	8.7 (1.89)	0.00317	3%
50–55 kHz	rs3688780	3	10 (2.17)	0.00155	3%
	rs13459177	15	7.6 (1.65)	0.00599	3%

ISSN: 2730-6844