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Table 1 Estimated parameters of the QTL identified by GLMM compared to true values in the simulation.

From: Generalized linear mixed model for segregation distortion analysis

  True effect True proportion Estimate StdErr Position (cM) LOD Proportion
QTL 1 1.4135 0.1543 1.1905 0.1357 50 16.6828 0.1224
QTL 2 -0.9993 0.0771 -0.8296 0.1252 125 9.5271 0.0594
QTL 3 0.9993 0.0771 0.9605 0.1328 360 11.3536 0.0796
QTL 4 -1.2048 0.1121 -1.1991 0.1353 905 17.0304 0.1241
QTL 5 1.0000 0.0772 0.8593 0.1310 1735a 9.3347 0.0637
QTL 6 -1.41354 0.1543 -1.2959 0.1380 2115 19.1230 0.1450
Co-factor 1 1.0000 0.1545 1.0217 0.1020 -- 21.7673 0.1803
Co-factor 2 1.0000 0.0386 1.1007 0.1809 -- 8.0412 0.0523
   0.8455b      0.8272c
  1. a1735 The true location is 1750 cM and the estimated location is 15 cM away from the true location.
  2. b0.8455 This is the true (total) proportion of the liability variance contributed by the six QTL and the two co-factors.
  3. c0.8272 This is the estimated (total) proportion of the liability variance contributed by the six QTL and the two co-factors.