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Table 1 Demographic, parasitological, and clinical characteristics of the study participants upon enrolment

From: Polymorphic variability in the 3' untranslated region (UTR) of IL12B is associated with susceptibility to severe anaemia in Kenyan children with acute Plasmodium falciparum malaria

Characteristic Non-SMA SMA P
Participants, n 304 240 N/A
Gender, female, n (%) 140 (46.1) 122 (50.8) 0.268a
Age, months 11 (10) 8 (7) <0.001 b
Axillary temperature, °C 37.5 (1.7) 37.4 (1.5) <0.001 b
Haemoglobin, g/dL 7.8 (2.7) 4.9 (1.4) <0.001 b
White blood cells, (×109/L) 10.9 (5.4) 13.1 (7.9) <0.001 b
Parasite density,/μL 19,932 (40,097) 17,262 (41,739) 0.446b
Geomean parasitaemia,/μL 14,486 12,598 0.678c
High-density parasitaemia, n (%) 201 (66.1) 142 (59.2) 0.057a
Sickle-cell trait, n (%) 49 (16.1) 6 (2.5) 0.054a
  1. Data are median values (interquartile range; IQR) unless otherwise noted. Children with P. falciparum malaria (n = 544) were categorized according to SMA status based on age- and geographically-appropriate Hb concentrations [i.e., Hb<6.0 g/dL, with any density parasitaemia) [4]] and non-SMA (Hb≥6.0 g/dL, with any density parasitaemia). High density parasitaemia (≥10,000 parasites/μL). aStatistical significance determined by Chi-square analysis. bStatistical significance determined by Mann-Whitney U test. cStatistical significance determined by independent groups t-test.