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Figure 4 | BMC Genetics

Figure 4

From: Identification of a second gene associated with variation in vertebral number in domestic pigs

Figure 4

Genomic structure of the QTL region for number of vertebrae. A. BAC clones used for swine genome sequencing by the International Swine Genome Sequencing Consortium. B. Gene map and microsatellite markers. In humans, VRTN has been submitted to public databases as C14orf115 encoding a hypothetical protein. Small triangles indicate positions of microsatellite markers. Double-headed arrows show conserved regions. For the 19 Q alleles of the Large White population (AY population), the haplotypes at seven markers from SJ7121 to SJ7103 were conserved. For the 14 Q alleles in the F2 families, the haplotypes at six markers from SJ7088 to SJ7114 were conserved. C. The QTL interval defined by haplotype analyses with microsatellite markers. The VRTN gene consisted of two exons (boxes) and was located in this interval. The shadowed box is the coding region. White triangles indicate positions of microsatellite markers and black triangles indicate polymorphic sequence-tagged sites (STSs). Numbers in parentheses are numbers of polymorphic sites at each STS. A total of 42 polymorphic sites, which formed two major haplotypes in the AY population, were present. Candidate sites are boxed. Information on polymorphisms is given in Table 3. The sequence of this region was submitted to GenBank/EMBL/DDBJ as AB554652.

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