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Table 3 Estimated allele substitution effects (standard error in parenthesis) of six SNPs in the bovine GNAS domain on growth performance and size

From: DNA sequence polymorphisms within the bovine guanine nucleotide-binding protein Gs subunit alpha (Gsα)-encoding (GNAS) genomic imprinting domain are associated with performance traits

SNP

Allele substitution

Culled cow carcass weight (kg)

Progeny carcass conformation1 (×100)

Progeny carcass fat2 (×100)

Stature3

(×10)

Body depth3 (×10)

Angularity3 (×10)

rs43101491

G→T

1.17

(1.06)

0.07

(3.40)

-4.07

(2.96)

-0.93

(1.52)

-0.47

(1.42)

-1.90

(1.59)

rs43101493

A→G

-0.13

(0.76)

-2.03

(2.45)

2.91

(2.12)

0.10

(1.07)

0.31

1.01

0.51

(1.13)

rs43101486

A→G

-0.23

(0.83)

0.20

(2.69)

-1.64

(2.34)

-1.08

(1.20)

-0.28

(1.13)

-0.90

(1.27)

rs43101485

C→G

0.10

(0.75)

1.87

(2.42)

-2.70

(2.11)

0.01

(1.07)

-1.83

(1.00)

-0.29

(1.13)

rs41694646

C→G

-1.66**

(0.65)

5.49**

(2.11)

5.44**

(1.82)

-2.97***

(0.92)

-2.88***

(0.87)

-1.87

(0.97)

rs41694656

A→G

0.40

(0.88)

-1.65

(2.84)

0.34

(2.45)

-4.93

(1.30)

-1.09

(1.22)

-1.15

(1.39)

  1. Significance of difference from zero = P ≤ 0.10; * = P ≤ 0.05; ** = P ≤ 0.01; *** = P ≤ 0.001.
  2. 1 Scale: 1 (poor)-15 (good)
  3. 2 Scale 1 (low)-15 (high)
  4. 3 Expressed in genetic standard deviation units.
  5. Underlined values represent genotype-phenotype associations that have remained statistically significant (q ≤ 0.05) after adjustment for multiple testing.