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Table 2 Estimated allele substitution effect (standard error in parenthesis) between six SNPs in the bovine GNAS domain and milk performance, somatic cell count (SCC), calving and fertility traits

From: DNA sequence polymorphisms within the bovine guanine nucleotide-binding protein Gs subunit alpha (Gsα)-encoding (GNAS) genomic imprinting domain are associated with performance traits

SNP Allele substitution Milk yield (kg) Milk protein yield (kg) Milk fat content1 (%×100) Milk protein content1 (%×100) SCC (units×100) Direct calving difficulty2 Maternal calving difficulty2 Gestation (days)
rs43101491 G→T 8.65
(16.56)
0.25
(0.46)
-1.25
(1.25)
-0.10
(0.61)
0.97
(1.01)
-0.51**
(0.19)
0.66**
(0.23)
-0.12
(0.12)
rs43101493 A→G 4.24
(12.05)
0.16
(0.33)
0.85
(0.91)
0.13
(0.44)
-0.97
(0.73)
0.08
(0.14)
-0.19
(0.17)
0.05
(0.09)
rs43101486 A→G -8.94
(13.58)
-0.05
(0.38)
0.11
(1.03)
0.37
(0.50)
1.36
(0.81)
-0.16
(0.16)
0.26
(0.19)
-0.04
(0.10)
rs43101485 C→G -2.61
(12.04)
-0.09
(0.34)
-0.85
(0.91)
-0.12
(0.44)
0.90
(0.72)
-0.12
(0.14)
0.19
(0.17)
-0.06
(0.09)
rs41694646 C→G -34.63***
(10.48)
-0.63*
(0.29)
1.98*
(0.79)
0.94*
(0.38)
-0.60
(0.63)
-0.44***
(0.12)
0.28
(0.15)
-0.23**
(0.08)
rs41694656 A→G 20.22
(14.04)
0.63
(0.39)
-0.79
(1.06)
-0.02
(0.52)
-2.37**
0.85
0.10
(0.17)
-0.29
(0.20)
0.01
(0.11)
  1. Significance of difference from zero = P ≤ 0.10; * = P ≤ 0.05; ** = P ≤ 0.01; *** = P ≤ 0.001.
  2. 1 A value of 1, prior to multiplication by 100, equates to 1 percentage unit.
  3. 2 Expressed in standard genetic deviation units.
  4. Underlined values represent genotype-phenotype associations that have remained statistically significant (q ≤ 0.05) after adjustment for multiple testing.