Table 6 Selected SNPs in the final HLA predictive models and their prediction accuracies
From: Empirical evaluations of analytical issues arising from predicting HLA alleles using multiple SNPs
| Â | Â | Selected SNPs | Accuracy%(Call Rate%) | |||||
|---|---|---|---|---|---|---|---|---|
| Â | HLA- | Count | start | Stop | Length | CT = 0 | CT = 0.5 | CT = 0.9 |
Intermediate Resolution | A | 33 | 29,850,894 | 30,111,284 | 260,390 | 98 | 99(97) | 99(89) |
| Â | B | 57 | 31,267,324 | 31,554,345 | 287,021 | 95 | 95(99) | 96(90) |
| Â | C | 36 | 31,280,634 | 31,458,359 | 177,725 | 99 | 99(100) | 99(93) |
| Â | DRB1 | 33 | 32,506,503 | 32,793,404 | 286,901 | 98 | 98(100) | 99(81) |
| Â | DQB1 | 20 | 32,444,139 | 32,778,222 | 334,083 | 98 | 98(100) | 99(94) |
| Â | DPB1 | 64 | 33,106,707 | 33,249,258 | 142,551 | - | - | - |
High Resolution | A | 59 | 29,918,924 | 30,171,347 | 252,423 | 96 | 97(95) | 97(79) |
| Â | B | 85 | 31,370,902 | 31,561,526 | 190,624 | 94 | 95 (95) | 96 (81) |
| Â | C | 50 | 31,187,623 | 31,444,736 | 257,113 | 98 | 98(99) | 98(86) |
| Â | DRB1 | 41 | 32,477,466 | 32,811,823 | 334,357 | 91 | 94(92) | 98(49) |
| Â | DQB1 | 28 | 32,517,462 | 32,870,439 | 352,977 | 98 | 98(98) | 98(92) |
| Â | DPB1 | 69 | 33,093,572 | 33,290,873 | 197,301 | - | - | - |