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Table 3 Association of the SNPs in the candidate genes with chicken AFE

From: Genetic effects of polymorphisms in candidate genes and the QTL region on chicken age at first egg

No.

Candidate gene

Sites1

Genotype

N2

AFE3

P value

M1

GnRH-I

G840327C

CC

26

135.1 ± 3.2A

0.0002**

   

GC

208

121.2 ± 1.1B

 
   

GG

972

123.6 ± 0.5B

 

M2

NPY

C31394761T

CC

392

121.5 ± 0.8a

0.0143*

   

TC

600

124.1 ± 0.7b

 
   

TT

214

125.0 ± 1.1b

 

M3

DRD2

T5841629C

CC

1060

123.2 ± 0.5a

0.0390*

   

TC

217

126.2 ± 1.1b

 
   

TT

5

119.2 ± 7.4ab

 

M4

VIP

G51389822T

GG

74

123.6 ± 1.9

0.3271

   

GT

400

124.4 ± 0.8

 
   

TT

732

122.8 ± 0.6

 

M5

VIPR-1

A1661691G

GG

1028

123.9 ± 0.5a

0.0390*

   

GA

95

121.4 ± 1.7ab

 
   

AA

83

119.7 ± 1.8b

 

M6

VIPR-1

C1704887T

CC

1128

123.2 ± 0.5

0.2022

   

TC

72

125.7 ± 2.0

 
   

TT

6

132.0 ± 6.7

 

M7

VIPR-1

C1715301T

CC

842

123.9 ± 0.6

0.2648

   

TC

252

122.1 ± 1.0

 
   

TT

112

122.6 ± 1.6

 

M8

PRL

I59724210D

II

10

126.2 ± 5.2

0.1851

   

ID

187

121.4 ± 1.2

 
   

DD

1009

123.7 ± 0.5

 
  1. 1The sites were referred to the chicken genome sequences released in May, 2006 http://genome.ucsc.edu/cgi-bin/hgGateway;
  2. 2N indicated the number of tested chickens of each genotype;
  3. 3AFE = age at first egg, the values are least-square means ± standard errors (SE).
  4. a,bWithin a column, for each site, measurements with no common superscripts are significantly different in single marker analysis, but not significantly different after Bonferroni correction (0.0042 < P < 0.05);
  5. A,BWithin a column, for each site, measurements with no common superscripts are great significantly different (P < 0.00083); * and ** indicate 0.0042 < P < 0.05 and P < 0.00083, respectively.