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Table 3 Power to Select Top Single-Nucleotide Polymorphisms in Stage One for Replication Based on 1,000 Replicates

From: A powerful hybrid approach to select top single-nucleotide polymorphisms for genome-wide association study

Number of Selections

p-Value-Based Ranking Approach

Hybrid Ranking Approach

 

M1

M2

M1

M2

10

52.2%

87.0%

88.9%

84.2%

20

57.9%

90.9%

89.9%

87.0%

30

61.1%

92.4%

90.4%

90.4%

40

62.6%

93.0%

91.2%

90.9%

  1. OR = odds ratio.
  2. MAF was set at 10% for M1 and 40% for M2.