Comparative analysis of copy number variation detection methods and database construction

BMC Genomic Data

Table 7 Average conservation score of start and end of CNV regions

Regions	Average conservation score in start regions	Average conservation score in end regions
Random ± 500bp	62.7	67.8
Random ± 800bp	60.9	77.0
Random ± 1kbp	69.1	76.0
CNVCommon1 ± 500bp	38.2	51.1
CNVCommon1 ± 800bp	42.5	55.6
CNVCommon1 ± 1kbp	47.9	62.3
CNVCommon2 ± 500bp	32.9	47.6
CNVCommon2 ± 800bp	35.7	50.8
CNVCommon2 ± 1kbp	39.4	57.0

CNVcommon1: 315 CNV regions detected by at least two programs and more than once.
CNVcommon2: 121 CNV regions detected by PennCNV more than four times and at least one other program
Scored sum value of phastCons44wayPrimates (UCSC) is used as Conservation score.
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ISSN: 2730-6844