Figure 2

Partial sequence from exon three of POMC. a) The 12 bp that are deleted and the affected amino acids in red, the first position in the valine codon and the 2nd and 3rd positions of the second alanine are coloured blue and POMC c.288C>T is coloured green. Purple represents the KR cleavage site b) the same sequence minus the 12 bps and 4 amino acids showing how the DNA and protein sequence comes back into alignment.