TY - JOUR AU - Eversley, Chevonne D. AU - Clark, Tavia AU - Xie, Yuying AU - Steigerwalt, Jill AU - Bell, Timothy A. AU - de Villena, Fernando PM AU - Threadgill, David W. PY - 2010 DA - 2010/11/03 TI - Genetic mapping and developmental timing of transmission ratio distortion in a mouse interspecific backcross JO - BMC Genetics SP - 98 VL - 11 IS - 1 AB - Transmission ratio distortion (TRD), defined as statistically significant deviation from expected 1:1 Mendelian ratios of allele inheritance, results in a reduction of the expected progeny of a given genotype. Since TRD is a common occurrence within interspecific crosses, a mouse interspecific backcross was used to genetically map regions showing TRD, and a developmental analysis was performed to identify the timing of allele loss. SN - 1471-2156 UR - https://doi.org/10.1186/1471-2156-11-98 DO - 10.1186/1471-2156-11-98 ID - Eversley2010 ER -