Table 2 SNP allele frequencies between cases and controls
From: Genetic predisposition for femoral neck stress fractures in military conscripts
Gene | Sequence variation | Detection method | Allele | Allele frequencies (%) | p-value | |
|---|---|---|---|---|---|---|
Controls | Cases | |||||
VDR | c.2T > C, Met1Thr (rs10735810) | Fok I | C | 153 (64) | 90 (62) | |
T | 87 (36) | 54 (37) | NS | |||
c.1024+283G > A (rs1544410) | Bsm I | A | 90 (38) | 45 (31) | ||
G | 150 (63) | 99 (69) | NS | |||
c.1056T > C, Ile352Ile (rs731236) | Taq I | C | 88 (37) | 45 (31) | ||
T | 152 (63) | 99 (69) | NS | |||
IL6 | -174G > C (rs1800795) | Nla III | C | 126 (52.5) | 72 (50) | |
G | 114 (47.5) | 72 (50) | NS | |||
CTR | c.1377C > T, Pro463Leu (rs1801197) | Alu I | C | 73 (30) | 35 (24) | |
T | 167 (70) | 109 (76) | NS | |||
COL1A1 | c.101+1024G > T (rs1800012) | Sequencing | G | 204 (85) | 123 (85) | |
T | 36 (15) | 21 (15) | NS | |||
c.1930-14T > C (rs2696247) | CSGE | C | 41 (17) | 28 (19) | ||
T | 199 (83) | 116 (81) | NS | |||
c.3261C > T (rs2586488) | Eco57 I | C | 158 (66) | 87 (60) | ||
T | 82 (34) | 57 (40) | NS | |||
COL1A2 | c.280-68A > G (rs406226) | CSGE | A | 206 (86) | 120 (83) | |
G | 34 (14) | 24 (17) | NS | |||
c.1666-41G > A (rs2301643) | Msl I | A | 32 (13) | 24 (17) | ||
G | 208 (87) | 120 (83) | NS | |||
c.2350-89ins38bp (rs3216902) | CSGE | insertion | 151 (63) | 96 (67) | ||
no ins. | 89 (37) | 48 (33) | NS | |||
LRP5 | c.2007G > A, E644E (rs2277268) | Sequencing | G | 231 (96) | 131 (91) | |
A | 9 (4) | 13 (9) | 0.031 1 | |||
c.2074G > A, V667M (rs4988321) | Sequencing | G | 235 (98) | 137 (95) | ||
A | 5 (2) | 7 (5) | NS | |||
c.3432A > G, V1119V (rs556442) | Sequencing | A | 200 (83) | 112 (78) | ||
G | 40 (17) | 32 (22) | NS | |||
c.4064C > T, A1330V (rs3736228) | Sequencing | C | 227 (95) | 134 (93) | ||
T | 13 (5) | 10 (7) | NS | |||