Model
|
without PC adjustment
|
with PC adjustment
|
---|
Single-SNP tests*
|
1.070
|
1.077
|
Main-effects
|
1.101
|
1.059
|
Main+adj
|
1.092
|
1.052
|
Haplotype
|
1.064
|
1.037
|
- Comparison of inflation in median test statistics () for each model with and without principal components. *Single-SNP tests without PC adjustment were Cochran-Armitage trend statistics which are not able to incorporate PC adjustment. The single-SNP statistics with PC adjustment are the 1 d.f. logistic regression.