TY - JOUR AU - Wason, James MS AU - Dudbridge, Frank PY - 2010 DA - 2010/09/09 TI - Comparison of multimarker logistic regression models, with application to a genomewide scan of schizophrenia JO - BMC Genetics SP - 80 VL - 11 IS - 1 AB - Genome-wide association studies (GWAS) are a widely used study design for detecting genetic causes of complex diseases. Current studies provide good coverage of common causal SNPs, but not rare ones. A popular method to detect rare causal variants is haplotype testing. A disadvantage of this approach is that many parameters are estimated simultaneously, which can mean a loss of power and slower fitting to large datasets. SN - 1471-2156 UR - https://doi.org/10.1186/1471-2156-11-80 DO - 10.1186/1471-2156-11-80 ID - Wason2010 ER -