Association of HPA axis-related genetic variation with stress reactivity and aggressive behaviour in pigs

BMC Genomic Data

Table 4 Association of candidate gene DNA markers with aggressive behaviour in the synthetic (SYN) line

Gene	Genotype		Genotype		Genotype		p-value
Trait	LSM^1,2	SE¹	LSM	SE	LSM	SE	q-value³
	(n)		(n)		(n)
*RYR1* c.1843C>T	CC		CT		TT
Rear Lesions (log ₁₀ LS)	0.87	0.027	0.95	0.035	na⁴		0.032
	(255)		(132)				0.19
*CRH* g.233C>T	CC		CT		TT
Rear Lesions (log ₁₀ LS)	0.86^e	0.035	0.92	0.031	0.99^f	0.051	0.085
	(134)		(189)		(61)		0.33
*CRHBP* c.51G>A	GG		GA		AA
Middle Lesions (log ₁₀ LS)	1.22	0.026	1.31	0.051	na		0.060
	(329)		(69)				0.27
*NR3C1* *c.2122A>G**	AA		AG		GG
Total Lesions (log ₁₀ LS)	1.69^e	0.035	1.68^e	0.024	1.59^f	0.033	0.045
	(80)		(174)		(83)		0.24
Front Lesions (log ₁₀ LS)	1.15^c	0.046	1.12^c	0.032	0.99^d	0.044	0.012
	(85)		(190)		(88)		0.13
*AVPR1B* c.1084A>G	AA		AG		GG
Total Lesions (log ₁₀ LS)	1.68	0.021	1.57	0.034	na		0.003
	(271)		(82)				0.04
Front Lesions (log ₁₀ LS)	1.11	0.028	1.02	0.047	na		0.061
	(295)		(86)				0.27
Middle Lesions (log ₁₀ LS)	1.25	0.026	1.13	0.045	na		0.007
	(309)		(90)				0.08
*UCN* g.1329T>C	TT		TC		CC
Front Lesions (log ₁₀ LS)	1.07	0.028	1.17	0.045	na		0.029
	(285)		(90)				0.19

¹LSM: least square mean; SE: standard error
²LSM with different superscripts ^{a,b; c,d; e,f} differ at p < 0.01; p < 0.05; and p < 0.1 respectively
³q-value: false discovery rate
⁴na: not available or not analyzed due to low frequency n < 10;

ISSN: 2730-6844