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Table 3 Association of candidate gene DNA markers with weight of the adrenal gland in the PiF1a line

From: Association of HPA axis-related genetic variation with stress reactivity and aggressive behaviour in pigs

Gene

Genotype

 

Genotype

 

Genotype

  

Trait*

LSM1,2

SE2

LSM

SE

LSM

SE

p-value

 

(n)

 

(n)

 

(n)

 

q-value3

RYR1 c.1843C>T

CC

 

CT

 

TT

  

Adrenal Weight (g)

2.29

0.03

2.22

0.03

na4

 

0.073

 

(98)

 

(107)

   

0.31

POMC c.293_298del

InsIns

 

InsDel

 

DelDel

  

Adrenal Weight (g)

2.24

0.02

2.40

0.07

na

 

0.027

 

(179)

 

(22)

   

0.19

MC2R c.306T>G

TT

 

TG

 

GG

  

Adrenal Weight (g)

2.11

0.04

2.31

0.03

na

 

<0.0001

 

(59)

 

(142)

   

<0.0001

NR3C1 c.*2122A>G

AA

 

AG

 

GG

  

Adrenal Weight (g)

2.11a

0.05

2.29b

0.03

2.30b

0.05

0.003

 

(42)

 

(119)

 

(45)

 

0.04

UCN g.1329T>C

TT

 

TC

 

CC

  

Adrenal Weight (g)

2.21

0.03

2.33

0.04

na

 

0.019

 

(146)

 

(54)

   

0.17

CRHR2 c.*13T>C

TT

 

TC

 

CC

  

Adrenal Weight (g)

2.31e

0.04

2.24

0.03

2.18f

0.05

0.087

 

(77)

 

(91)

 

(38)

 

0.33

  1. 1LSM: least square mean; SE: standard error
  2. 2LSM with different superscripts a,b; c,d; e,f differ at p < 0.01; p < 0.05; and p < 0.1 respectively
  3. 3q-value: false discovery rate
  4. 4na: not available or not analyzed due to low frequency n < 10;