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Table 3 Allele substitution effect (standard error in parenthesis) between the 8 SNPs and survival in the herd, reproduction and calving performance

From: Association of bovine leptin polymorphisms with energy output and energy storage traits in progeny tested Holstein-Friesian dairy cattle sires

SNP

Allele

Survival in the herd (%)

Calving interval (days)

Direct calving difficulty (%)

Maternal calving difficulty (%)

Gestation length (days)

Calf Perinatal mortality (%)

Number of bulls

 

477

501

575

506

614

201

LEPR-T945M

C to T

-0.2833 (0.2395)

0.20 (0.44)

0.26 (0.20)

0.08 (0.25)

-0.06 (0.13)

-0.06 (0.16)

LEP-2470

C to T

-0.1036 (0.2060)

0.19 (0.37)

-0.02 (0.17)

0.11 (0.21)

-0.05 (0.11)

0.30 (0.13)*

LEP-1457

A to G

0.2072 (0.1290)

-0.07 (0.23)

-0.11 (0.12)

-0.07 (0.13)

-0.11 (0.07)

-0.12 (0.08)

LEP-1238

C to G

-0.2009 (0.1361)

0.07 (0.25)

0.24 (0.12)†

-0.12 (0.14)

0.16 (0.08)*

0.16 (0.09) †

LEP-963

C to T

0.1737 (0.1333)

-0.05 (0.24)

-0.30 (0.12)*

0.2 (0.14)

-0.17 (0.08)*

-0.14 (0.09)

Y7F

A to T

-0.1500 (0.3342)

0.11 (0.60)

-0.22 (0.28)

0.25 (0.33)

-0.33 (0.18) †

0.10 (0.23)

R25C

C to T

0.1550 (0.1348)

0.03 (0.24)

-0.28 (0.12)*

0.16 (0.14)

-0.18 (0.08)*

-0.10 (0.09)

A80V

C to T

-0.3049 (0.1476)*

0.29 (0.27)

0.11 (0.13)

0.00 (0.15)

0.05 (0.08)

0.08 (0.10)

  1. Significance of difference from zero† = P < 0.10; * = P < 0.05; ** = P < 0.01
  2. Because of complete linkage disequilibrium between phases among the SNPs LEP-1457, LEP-1609 and LEP-580, only LEP-1457 was retained for the association analysis