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Table 2 Genotype frequencies, minor allele frequencies (MAF) and significance of deviation from Hardy-Weinberg equilibrium (HWE) for the leptin and leptin receptor SNPs

From: Association of bovine leptin polymorphisms with energy output and energy storage traits in progeny tested Holstein-Friesian dairy cattle sires

Region

GenBank Accession No.

SNP

BTA

Position

Genotype

Genotype Frequency (%)

MAF (%)

HWE1

Receptor

AJ580801

LEPR-T945M

3

85691334

C/C

0.83

0.09

0.66

     

C/T

0.17

  
     

T/T

0.01

  

Promoter

AB070368

LEP-2470

4

95675400

C/C

0.75

0.13

0.25

     

C/T

0.24

  
     

T/T

0.01

  

Promoter

 

LEP-1457

4

95676411

A/A

0.27

0.48

1.00

     

A/G

0.50

  
     

G/G

0.23

  

Promoter

 

LEP-1238

4

95676628

C/C

0.14

0.37

0.57

     

C/G

0.45

  
     

G/G

0.40

  

Promoter

 

LEP-963

4

95676903

C/C

0.41

0.37

0.75

     

C/T

0.46

  
     

T/T

0.14

  

Coding

U50365

Y7F

4

95689996

A/A

0.93

0.04

0.08

  

(dsSNP rs29004487)

  

A/T

0.07

  
     

T/T

0.00

  

Coding

 

R25C

4

95690050

C/C

0.40

0.37

0.78

  

(dsSNP rs29004488)

  

C/T

0.47

  
     

T/T

0.13

  

Coding

 

A80V

4

95691973

C/C

0.49

0.29

0.05

  

(dsSNP rs29004508)

  

C/T

0.44

  
     

T/T

0.07

  
  1. 1Significance of the deviation from HWE derived using a chi-square test
  2. LEP-580 and LEP-1609 were omitted from the table as they exhibit complete linkage disequilbrium with LEP-1457