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Figure 4 | BMC Genetics

Figure 4

From: Calcineurin and Protein kinase G regulate C. elegans behavioral quiescence during locomotion in liquid

Figure 4

Model for action of EGL-4 and TAX-6 in regulation of the quiescent state. ACh = acetylcholine. Calcineurin (tax-6) facilitates maintenance of swimming by its activity in the sensory neurons. PKG (egl-4) and calcineurin (tax-6) acts antagonistically in the sensory neurons. In addition, egl-4 activity outside the sensory neurons antagonizes GABAergic activity that results in termination of quiescence. Alternatively egl-4 may activate a neurosecretory pathway in the sensory neurons that may block GABAergic neurotransmission.

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ISSN: 2730-6844

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