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Table 4 Simultaneous two-locus search without incorporating a covariate

From: Incorporation of covariates in simultaneous localization of two linked loci using affected relative pairs

 

ESTIMATE

(S.E.) or [95% CI]

 

Ï„1 (cM)

Ï„2 (cM)

C1

C2

λ 1

λ 2

Using one ARP only:

      

Full siblings

1.38

124.27

-0.04

0.12

1.25

1.44

 

(39.44)

(7.64)

[-0.17,0.10]

[-0.008,0.25]

[0.83,1.89]

[0.91,2.13]

Avuncular pairs

50.77

142.05

0.11

0.097

1.17

1.36

 

(0.73)

(13.42)

[-0.07,0.29]

[-0.03,0.22]

[0.80,1.69]

[0.83,1.95]

Using both ARPs:

      

Full siblings

  

0.06

0.12

1.17

1.40

   

[-0.07,0.18]

[-0.01,0.24]

[0.86,1.70]

[0.90,2.08]

Avuncular pairs

  

0.11

0.060

1.30

1.45

   

[-0.07,0.29]

[-0.034,0.154]

[0.55,2.40]

[0.68,2.28]

   Common τ

50.98

125.43

    
 

(0.72)

(6.84)

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