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Figure 2 | BMC Genetics

Figure 2

From: Single-nucleotide polymorphism, linkage disequilibrium and geographic structure in the malaria parasite Plasmodium vivax: prospects for genome-wide association studies

Figure 2

Variation in LD in relation to physical distance between SNP loci along chromosome 8 of P. vivax. Data are shown for Brazil (Granada, Plácido de Castro and Porto Velho combined), Cambodia, Sri Lanka, and Vietnam. LD was measured with the r2 statistic (values on y-axis are multiplied by 100); closed (blue) circles denote significant LD (χ2 statistic, P < 0.05), while open circles denote nonsignificant LD. A significant negative correlation between r2 values and physical distance between SNPs (in kb) was found only for Brazil (Pearson correlation coefficient r = -0.195, P < 0.0001).

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