Genome-wide linkage scan for loci associated with epilepsy in Belgian shepherd dogs

BMC Genomic Data

Table 1 Association of microsatellite markers with epilepsy in Belgian Tervuren dogs on chromosomal regions exhibiting suggestive linkage

CFA Position Mb	Marker	PIC	Two-Point Epilepsy^a	Two-Point Age at Onset^b	Multi-point LOD^c	Fisher Exact*	Cri-Map LOD	TDT*	Sib-Pair*	Hap block*
CFA02
7.16	FH2274	0.41	0.615	0.715	0.63	0.0018	0.02	0.002	0.175
10.35	v170	0.57	0.396	0.781	0.785	0.0001	0	0.000	0.333	0.04
15.5	v163	0.55	1.095	1.616	0.802	0.0005	0	0.000	0.413
43.23	v200	0.65	0.037	0.129	0.074	0.0067	0	0.388	0.142
46.62	v205	0.56	1.063	1.447	0.08	0.3283	0.24	0.005	0.144
69.34	v235	0.63	0.252	0.133	0.864	0.0104	0.24	0.002	0.56
73.02	v240	0.69	1.001	1.415	0.834	0.0076	0.84	0.001	0.097	0.05
78.35	AHT111	0.59	0.01	0.068	0.733	0.0003	0.38	0.009	0.542
81.01	FH3965	0.78	0.15	0.031	0.735	0.7088	1.13	0.363	0.102
CFA06
15.58	v620	0.41	1.057	1.024	0.236	0.6055	0.15	0.786	0.12	0.008
26.16	v633	0.34	0.251	0.362	0.015	0.6572	0	0.876	0.447
30.97	v639	0.70	0.073	0.161	0.004	0.0283	0.02	0.000	0.454
CFA12
24.28	1-21-3	0.68	0.719	0.79	0.625	0.114	0.31	0.000	0.999
24.28	FH2054	0.67	1.212	1.26	0.634	0.5973	0.83	0.010	0.464
27.72	FH2401	0.61	0.15	0.448	0.688	0.667	0	0.094	0.844
35.37	v1172	0.39	0	0.077	0.751	0.6036	0	0.010	0.905
44.55	FH3591	0.85	1.221	1.369	0.788	0.3102	0.2	0.002	0.929	0.035
CFA37
18.09	AHT133	0.53	0.048	0.066	0.217	0.0021	0	0.013	0.288	0.003
22.39	Ren67c18	0.59	0.391	0.528	0.960	0.007	0	0.016	0.025

^a Two-point LOD scores for the binary trait of epilepsy
^b Two-point LOD scores for the continuous trait of age at onset
^c Highest multipoint LOD score for the binary trait of epilepsy nearest the associated marker
*P-values

ISSN: 2730-6844