Figure 2

Functional analysis of the c.-582A variant. Cotransfection of HepG2 cells with pCMV-USF1, pCMV-USF2 or pCMV-USF1+ pCMV-USF2 (1:1) increased the promoter activation compared to cells transfected with VarG-Hep/Luc constructs alone (basal). Data represent means of three independent experiments (± SEM) ***p < 0.001